Learning from other autoimmunities to understand targeting of B cells to control multiple sclerosis

Author:

Baker David1,Pryce Gareth1,Amor Sandra12,Giovannoni Gavin13,Schmierer Klaus13

Affiliation:

1. BartsMS, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

2. Pathology Department, Free University Amsterdam, 1081 HV Amsterdam, The Netherlands

3. Clinical Board Medicine (Neuroscience), The Royal London Hospital, Barts Health NHS Trust, London, UK

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Reference191 articles.

1. CD20 therapies in multiple sclerosis and experimental autoimmune encephalomyelitis—targeting T or B cells?;Agahozo;Mult Scler Relat Disord,2016

2. Safety and tolerability of inebilizumab (MEDI–551), an anti-CD19 monoclonal antibody, in patients with relapsing forms of multiple sclerosis: results from a phase 1 randomised, placebo-controlled, escalating intravenous and subcutaneous dose study;Agius;Mult Scler,2017

3. HLA alleles modulate EBV viral load in multiple sclerosis;Agostini;J Transl Med,2018

4. Immunity 12 years after alemtuzumab in RA: CD5+ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses;Anderson;Rheumatology,2012

5. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy;Anolik;Arthritis Rheum,2007

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