Effects of amyloid pathology and neurodegeneration on cognitive change in cognitively normal adults

Author:

Bilgel Murat1,An Yang1,Helphrey Jessica1,Elkins Wendy1,Gomez Gabriela1,Wong Dean F2345,Davatzikos Christos6,Ferrucci Luigi7,Resnick Susan M1

Affiliation:

1. Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, USA

2. Section of High Resolution PET Imaging, Division of Nuclear Medicine, Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA

3. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA

4. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA

5. Department of Neurology and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA

6. Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, PA, USA

7. Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA

Funder

Intramural Research Program

National Institute on Aging

NIH

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Reference52 articles.

1. Test-retest stability on the WRAT-3 reading subtest in geriatric cognitive evaluations;Ashendorf;J Clin Exp Neuropsychol,2009

2. Cognitive impairment in preclinical Alzheimer’s disease: a meta-analysis;Bäckman;Neuropsychology,2005

3. Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: a meta-analysis;Baker;Alzheimers Dement,2016

4. Clinical and biomarker changes in dominantly inherited Alzheimer’s disease;Bateman;N Engl J Med,2012

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