Invited Commentary: Detecting Individual and Global Horizontal Pleiotropy in Mendelian Randomization—A Job for the Humble Heterogeneity Statistic?
Author:
Affiliation:
1. MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom
Funder
Medical Research Council
Publisher
Oxford University Press (OUP)
Subject
Epidemiology
Link
http://academic.oup.com/aje/advance-article-pdf/doi/10.1093/aje/kwy185/25997032/kwy185.pdf
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3. One hundred years of pleiotropy: a retrospective;Stearns;Genetics,2010
4. Mendelian randomization: genetic anchors for causal inference in epidemiological studies;Davey Smith;Hum Mol Genet,2014
5. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases;Verbanck;Nat Genet,2018
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