Implementation of a screening and management pathway for chronic obstructive pulmonary disease in patients with atrial fibrillation

Author:

van der Velden Rachel M J1ORCID,Hereijgers Maartje J M1ORCID,Arman Nazia1,van Middendorp Naomi1,Franssen Frits M E234,Gawalko Monika15ORCID,Verhaert Dominique V M16ORCID,Habibi Zarina16ORCID,Vernooy Kevin16ORCID,Koltowski Lukasz5ORCID,Hendriks Jeroen M78ORCID,Heidbuchel Hein91011ORCID,Desteghe Lien9101112ORCID,Simons Sami O34,Linz Dominik16813ORCID

Affiliation:

1. Department of Cardiology, Maastricht University Medical Centre and Cardiovascular Research Institute Maastricht , P. Debyelaan 25, 6229 HX Maastricht , the Netherlands

2. Department of Research and Development, Ciro , 6085 NM Horn , the Netherlands

3. NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University , 6200 MD Maastricht , the Netherlands

4. Department of Respiratory Medicine, Maastricht University Medical Centre , 6229 HX Maastricht , the Netherlands

5. 1st Department of Cardiology, Medical University of Warsaw , 02-091 Warsaw , Poland

6. Department of Cardiology, Radboud University Medical Centre , 6525 GA Nijmegen , the Netherlands

7. Caring Futures Institute, College of Nursing and Health Sciences, Flinders University , 5001 Adelaide , Australia

8. Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , 5000 Adelaide , Australia

9. Department of Cardiology, Antwerp University Hospital , 2650 Antwerp , Belgium

10. Research Group Cardiovascular Diseases, University of Antwerp , 2650 Antwerp , Belgium

11. Faculty of Medicine and Life Sciences, Hasselt University , 3590 Hasselt , Belgium

12. Heart Center Hasselt, Jessa Hospital , 3500 Hasselt , Belgium

13. Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen , 2200 Copenhagen , Denmark

Abstract

Abstract Aims Chronic obstructive pulmonary disease (COPD) negatively impacts the efficacy of heart rhythm control treatments in patients with atrial fibrillation (AF). Although COPD is recognized as a risk factor for AF, practical guidance about how and when to screen for COPD is not available. Herein, we describe the implementation of an integrated screening and management pathway for COPD into the existing pre-ablation work-up in an AF outpatient clinic infrastructure. Methods and results Consecutive unselected patients accepted for AF catheter ablation in the Maastricht University Medical Center+ were prospectively screened for airflow limitation using handheld (micro)spirometry at the pre-ablation outpatient clinic supervised by an AF nurse. Patients with results suggestive of airflow limitation were offered referral to the pulmonologist. Handheld (micro)spirometry was performed in 232 AF patients, which provided interpretable results in 206 (88.8%) patients. Airflow limitation was observed in 47 patients (20.3%). Out of these 47 patients, 29 (62%) opted for referral to the pulmonologist. The primary reason for non-referral was low perceived symptom burden. Using this screening strategy 17 (out of 232; 7.3%) ultimately received a diagnosis of chronic respiratory disease, either COPD or asthma. Conclusion A COPD care pathway can successfully be embedded in an existing AF outpatient clinic infrastructure, using (micro)spirometry and remote analysis of results. Although one out of five patients had results suggestive of an underlying chronic respiratory disease, only 62% of these patients opted for a referral. Pre-selection of patients as well as patient education might increase the diagnostic yield and requires further research.

Funder

Dutch Heart Foundation

European Commission

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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