Impact of centre volume on atrial fibrillation ablation outcomes in Europe: a report from the ESC EHRA EORP Atrial Fibrillation Ablation Long-Term (AFA LT) Registry

Author:

Vassilikos Vassilios P1ORCID,Pagourelias Efstathios D1,Laroche Cécile2,Blomström-Lundqvist Carina3,Kautzner Josef4,Maggioni Aldo P25,Tavazzi Luigi6,Dagres Nikolaos7,Brugada Josep8,Stühlinger Markus9,Arbelo Elena101112,

Affiliation:

1. Third Department of Cardiology, Hippokrateion General Hospital, Medical School, Aristotle University of Thessaloniki, 49 Konstantinoupoleos str, 54642 Thessaloniki, Greece

2. EURObservational Research Programme (EORP), European Society of Cardiology, Sophia-Antipolis, France

3. Department of Medical Science and Cardiology, Uppsala University, Uppsala, Sweden

4. Department of Cardiology, Institute for Clinical and Experimental Medicine (ΙΚΕΜ), Prague, Czech Republic

5. ANMCO Research Centre, Florence, Italy

6. Cardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy

7. Department of Electrophysiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany

8. Hospital Clínic Pediatric Arrhythmia Unit, Cardiovascular Institute, Hospital Sant Joan de Déu University of Barcelona, Barcelona, Spain

9. Clinic of Internal Medicine III/Cardiology, Medical University of Innsbruck, Innsbruck, Austria

10. Department of Cardiology, Cardiovascular Institut, Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain

11. Instit d’Investigació August Pi i Sunyer (IDIBAPS), Barcelona, Spain

12. Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain

Abstract

Abstract Aims  The aim of the study was to investigate differences in clinical outcomes and complication rates among European atrial fibrillation (AF) ablation centres related to the volume of AF ablations performed. Methods and results  Data for this analysis were extracted from the ESC EHRA EORP European AF Ablation Long-Term Study Registry. Based on 33rd and 67th percentiles of number of AF ablations performed, the participating centres were classified into high volume (HV) (≥ 180 procedures/year), medium volume (MV) (<180 and ≥74/year), and low volume (LV) (<74/year). A total of 91 centres in 26 European countries enrolled in 3368 patients. There was a significantly higher reporting of cardiovascular complications and stroke incidence in LV centres compared with HV and MV (P = 0.039 and 0.008, respectively) and a lower success rate after AF ablation (55.3% in HV vs. 57.2% in LV vs. 67.4% in MV centres, P < 0.001), despite lower CHA2DS2-VASc score of patients, enrolled in LVs and less complex ablation techniques used. Adjustments of confounding factors (including type of AF ablation) led to elimination of these differences. Conclusion  Low-volume centres tended to present slightly higher cardiovascular complications’ and stroke incidence and a lower unadjusted success rate after AF ablation, despite the fact that ablation procedures and patients were of lower risk compared with MV and HV centres. On the other hand, adjusted overall complication and recurrence rates were non-significantly different among different volume centres, a fact reflecting the heterogeneity of patient and procedural profiles, and a counterbalance between expertise and risk level among participating centres.

Funder

Abbott Vascular Int.

AstraZeneca

Bayer AG

The Bristol Myers Squibb and Pfizer Alliance

Daiichi Sankyo Europe GmbH

The Alliance Daiichi Sankyo Europe GmbH and Eli Lilly and Company

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3