Miniseries 2—septal and paraseptal accessory pathways—part II: para-Hisian accessory pathways—so-called anteroseptal pathways revisited

Author:

Farré Jerónimo1,Anderson Robert H2ORCID,Sánchez-Quintana Damián3,Mori Shumpei4ORCID,Rubio José-Manuel1,García-Talavera Camila1,Bansal Raghav5ORCID,Lokhandwala Yash6,Cabrera José-Angel78,Wellens Hein J J9,Sternick Eduardo Back10ORCID

Affiliation:

1. Fundación Jiménez Díaz University Hospital, Institute of Biomedical Research, Madrid, Spain

2. Institute of Biosciences, Newcastle University, Newcastle upon Tyne, UK

3. Department of Anatomy and Cell Biology, Universidad de Extremadura, Badajoz, Spain

4. UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

5. All India Institute of Medical Sciences (AIIMS), New Delhi, India

6. Arrhythmia Associates, Mumbai, India

7. Unidad de Arritmias, Departamento de Cardiología, Hospital Universitario Quirón-Salud, Madrid, Spain

8. Complejo Hospitalario Ruber Juan Bravo, Universidad Europea de Madrid, Madrid, Spain

9. CARIM—Cardiovascular Research Centre, Maastricht, The Netherlands

10. Arrhythmia and Electrophysiology Department, Biocor Instituto, Nova Lima, Minas Gerais, Brazil

Abstract

Abstract Surgeons, when dividing bypass tracts adjacent to the His bundle, considered them to be ‘anteroseptal’. The area was subsequently recognized to be superior and paraseptal, although this description is not entirely accurate anatomically, and conveys little about the potential risk during catheter interventions. We now describe the area as being para-Hisian, and it harbours two types of accessory pathways. The first variant crosses the membranous septum to insert into the muscular ventricular septum without exiting the heart, and hence being truly septal. The second variant inserts distally in the paraseptal components of the supraventricular crest, and consequently is crestal. The site of ventricular insertion determines the electrocardiographic expression of pre-excitation during sinus rhythm, with the two types producing distinct patterns. In both instances, the QRS and the delta wave are positive in leads I, II, and aVF. In crestal pathways, however, the QRS is ≥ 140 ms, and exhibits an rS configuration in V1–2. The delta wave in V1–2 precedes by 20–50 ms the apparent onset of the QRS in I, II, III, and aVF. In the true septal pathways, the QRS complex occupies ∼120 ms, presenting a QS, W-shaped, morphology in V1–2. The delta wave has a simultaneous onset in all leads. Our proposed terminology facilitates the understanding of the electrocardiographic manifestations of both types of para-Hisian pathways during pre-excitation and orthodromic tachycardia, and informs on the level of risk during catheter ablation.

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference23 articles.

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