Clinical practice and implementation of guidelines for the prevention, diagnosis and management of cardiac implantable electronic device infections: results of a worldwide survey under the auspices of the European Heart Rhythm Association

Author:

Traykov Vassil1ORCID,Bongiorni Maria Grazia2,Boriani Giuseppe3,Burri Haran4ORCID,Costa Roberto5ORCID,Dagres Nikolaos6ORCID,Deharo Jean-Claude7ORCID,Epstein Laurence M8,Erba Paola Anna9ORCID,Snygg-Martin Ulrika10,Nielsen Jens Cosedis11,Poole Jeanne E12ORCID,Saghy Laszlo13,Starck Christoph14ORCID,Strathmore Neil15,Blomström-Lundqvist Carina16

Affiliation:

1. Department of Invasive Electrophysiology and Cardiac Pacing, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria

2. Cardiology and Arrhythmology Division, CardioThoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy

3. Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy

4. Department of Cardiology, University Hospital of Geneva, Geneva, Switzerland

5. Department of Cardiovascular Surgery, Heart Institute (InCor) of the University of São Paulo, São Paulo, Brazil

6. Department of Electrophysiology, Heart Center Leipzig at the University of Leipzig, Leipzig, Germany

7. Department of Cardiology, Aix Marseille Université, CHU la Timone, Marseille, France

8. System Director, Electrophysiology, Northwell Health, Hofstra/Northwell School of Medicine, Manhasset, NY, USA

9. Department of Translational Research and New Technology in Medicine, University of Pisa, AOUP, Italy and Department on Nuclear Medicine & Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

10. Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

11. Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark

12. University of Washington, Cardiology, Seattle, WA, USA

13. Electrophysiology Division, 2nd Department of Medicine and Cardiology Centre, University of Szeged, Szeged, Hungary

14. Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany

15. Department of Cardiology, Royal Melbourne Hospital, Parkville, Australia

16. Department of Medical Science and Cardiology, Uppsala University, Uppsala, Sweden

Abstract

Abstract Aims Cardiac implantable electronic device (CIED) infection rates are increasing. Worldwide compliance and disparities to published guidelines for the prevention, diagnosis and management of these conditions are not well elucidated. The purpose of this survey, therefore, was to clarify these issues through an inquiry to arrhythmia-related associations and societies worldwide. Methods and results A questionnaire comprising 15 questions related to CIED infections was distributed among members of seven arrhythmia societies worldwide. A total of 234 centres in 62 countries reported implantation rates of which 159 (68.0%) performed more than 200 device implantations per year and 14 (6.0%) performed fewer than 50 implantations per year. The reported rates of CIED infections for 2017 were ≤2% in 78.7% of the centres, while the infection rates exceeded 5% in 7.8% of the centres. Preventive measures for CIED infection differed from published recommendations and varied among different regions mainly in terms of pocket irrigation and administering post-operative antimicrobial therapy the use of which was reported by 39.9% and 44% of the respondents, respectively. Antibacterial envelopes were used by 37.7% of the respondents in selected circumstances. In terms of pocket infection management, 62% of the respondents applied complete system removal as an initial step. Diagnostic pocket needle aspiration and pocket surgical debridement were reported by 15.8% and 11.8% of centres, respectively. Conclusion Clinical practices for prevention and management of CIED do not fully comply with current recommendations and demonstrate considerable regional disparities. Further education and programmes for improved implementation of guidelines are mandatory.

Funder

Abbott

Biotronik

Boston Scientific and Medtronic

Boehringer Ingelheim

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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