An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb-Reference-Cited by-同舟云学术

An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb

Published:2018-11-27 Issue:3 Volume:47 Page:1523-1531
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Shortridge Matthew D¹^ORCID,Wille Paul T²,Jones Alisha N¹,Davidson Amy¹,Bogdanovic Jasmina³,Arts Eric²,Karn Jonathan²,Robinson John A³,Varani Gabriele¹

Affiliation:

1. Department of Chemistry, University of Washington, Seattle, Washington 98195-1700

2. Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio 44106-4960

3. Department of Chemistry, University of Zurich, Zurich, Switzerland CH-8057

Funder

National Institute of General Medical Sciences

American Cancer Society

National Sleep Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/47/3/1523/27853662/gky1197.pdf

Reference56 articles.

1. Fragments of the HIV-1 Tat protein specifically bind TAR RNA;Weeks;Science,1990

2. Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge;Aboul-ela;Nucleic Acids Res.,1996

3. Visualizing transient low-populated structures of RNA;Dethoff;Nature,2012

4. Role of RNA structure in arginine recognition of TAR RNA;Puglisi;Proc. Natl. Acad. Sci. U.S.A.,1993

5. Dissection of the proposed base triple in human immunodeficiency virus TAR RNA indicates the importance of the Hoogsteen interaction;Tao;Biochemistry,1997

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