A translational silencing function of MCPIP1/Regnase-1 specified by the target site context

Author:

Behrens Gesine1,Winzen Reinhard1,Rehage Nina2,Dörrie Anneke1,Barsch Monika1,Hoffmann Anne3ORCID,Hackermüller Jörg34,Tiedje Christopher1,Heissmeyer Vigo25,Holtmann Helmut1

Affiliation:

1. Institute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany

2. Institute for Immunology, Biomedical Center of the Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany

3. Young Investigators Group Bioinformatics and Transcriptomics, Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, 04318 Leipzig, Germany

4. Department of Computer Science, University of Leipzig, 04081 Leipzig, Germany

5. Research Unit Molecular Immune Regulation, Helmholtz Zentrum München, 81377 München, Germany

Funder

Deutsche Forschungsgemeinschaft

Fritz Thyssen Foundation

Else Kroner-Fresenius Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference59 articles.

1. Post-transcriptional regulons coordinate the initiation and resolution of inflammation;Anderson;Nat. Rev. Immunol.,2010

2. Translational control of immune responses: from transcripts to translatomes;Piccirillo;Nat. Immunol.,2014

3. Regulation of T-cell signaling and autoimmunity by RNA-binding proteins;Jeltsch;Curr. Opin. Immunol.,2016

4. Posttranscriptional mechanisms regulating the inflammatory response;Stoecklin;Adv. Immunol.,2006

5. The role of mammalian MAPK signaling in regulation of cytokine mRNA stability and translation;Tiedje;J. Interferon Cytokine Res.,2014

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