Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module-Reference-Cited by-同舟云学术

Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module

Published:2018-02-20 Issue:8 Volume:46 Page:4241-4255
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Albrecht Todd R¹,Shevtsov Sergey P²,Wu Yixuan³,Mascibroda Lauren G¹,Peart Natoya J¹,Huang Kai-Lieh¹,Sawyer Iain A²⁴,Tong Liang³,Dundr Miroslav²,Wagner Eric J¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA

2. Department of Cell Biology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064, USA

3. Department of Biological Sciences, Columbia University, New York, NY 10027, USA

4. Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA

Funder

Welch Foundation

Cancer Prevention and Research Institute of Texas

NIH

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/8/4241/24782667/gky100.pdf

Reference58 articles.

1. Integrator: surprisingly diverse functions in gene expression;Baillat;Trends Biochem. Sci.,2015

2. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II;Baillat;Cell,2005

3. A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3′-end formation;Ezzeddine;Mol. Cell. Biol.,2011

4. Integrator mediates the biogenesis of enhancer RNAs;Lai;Nature,2015

5. Integrator regulates transcriptional initiation and pause release following activation;Gardini;Mol. Cell,2014

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