SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function

Author:

Du Yuzhang1,Hou Guofang12,Zhang Hailong1,Dou Jinzhuo1,He Jianfeng1,Guo Yanming1,Li Lian1,Chen Ran1,Wang Yanli1,Deng Rong1,Huang Jian1,Jiang Bin2,Xu Ming2,Cheng Jinke1,Chen Guo-Qiang3,Zhao Xian1,Yu Jianxiu134ORCID

Affiliation:

1. Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

2. Department of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, 280 Mohe Road, Shanghai 201999, China

3. Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

4. State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Genetics

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