Brain tumor research in the United Kingdom: current perspective and future challenges. A strategy document from the NCRI Brain Tumor CSG

Author:

Kurian Kathreena M1,Jenkinson Michael D23,Brennan Paul M4,Grant Robin4,Jefferies Sarah5,Rooney Alasdair G6,Bulbeck Helen7,Erridge Sara C8,Mills Samantha9,McBain Catherine10,McCabe Martin G11,Price Stephen J12,Marino Silvia13,Moyes Erica14,Qian Wendy15,Waldman Adam16,Vaqas Babar17,Keatley Debbie18,Burchill Peter18,Watts Colin12

Affiliation:

1. Institute of Clinical Neurosciences, University of Bristol, Learning and Research Building, Southmead Hospital, Bristol

2. Institute of Translational Medicine, University of Liverpool

3. Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK

4. Department of Clinical Neurosciences, Western General Hospital, Edinburgh

5. Department of Oncology, Cambridge University Hospitals, Foundation Trust, Cambridge, CB2, UK

6. Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh

7. brainstrust, the brain cancer people, Cowes, UK

8. Edinburgh Centre for Neuro-Oncology, Edinburgh Cancer Centre, Western General Hospital, Edinburgh

9. Blizard Institute, Barts and The London Medical School, Queen Mary University of London, London, UK

10. Manchester Academic Health Science Centre, University of Manchester, Manchester, UK

11. Department of Clinical Oncology, The Christie NHS Foundation Trust Hospital, Manchester, UK

12. Department of Clinical Neurosciences, Division of Neurosurgery, University of Cambridge, UK

13. Department of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool and Informatics, Imaging and Data Sciences, University of Manchester

14. The Brain Tumor Charity, Farnborough, UK

15. Cambridge Cancer Trials Centre | Cambridge Clinical Trials Unit—Cancer Theme, Cambridge University Hospitals NHS Foundation Trust

16. Imaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK

17. Department of Surgery, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London

18. Patient and Public Involvement Representative

Abstract

Abstract The National Cancer Research Institute (NCRI) is a partnership of charity and government research funders whose purpose is to improve health and quality of life by accelerating progress in cancer-related research through collaboration. Under this umbrella, the NCRI Brain Tumor Clinical Studies Group is focused on improving clinical outcomes for adult patients with brain and central nervous system tumors, including those with brain metastasis from other primary sites. This document discusses the current state of clinical brain tumor research in the United Kingdom and the challenges to increasing study and trial opportunities for patients. The clinical research priorities are defined along with a strategy to strengthen the existing brain tumor research network, improve access to tissue and imaging and to develop the future leadership for brain tumor research in the United Kingdom. This strategy document may serve as a framework for other organizations and countries.

Publisher

Oxford University Press (OUP)

Subject

Medicine (miscellaneous)

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