Mutant p53 in colon cancer
Author:
Affiliation:
1. Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
2. WPI-Nano Life Science Institute, Kanazawa University, Kanazawa, Japan
Funder
AMED-CREST
AMED
Japan Agency for Medical Research and Development
Ministry of Education, Culture, Sports, Science and Technology of Japan
Takeda Science Foundation
Mitsubishi Foundation
Publisher
Oxford University Press (OUP)
Subject
Cell Biology,Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/jmcb/article-pdf/11/4/267/28541826/mjy075.pdf
Reference83 articles.
1. A mutant-p53/Smad complex opposes p63 to empower TGFβ-induced metastasis;Adorno;Cell,2009
2. p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo;Alexandrova;Cell Death Dis.,2017
3. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment;Alexandrova;Nature,2015
4. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis;Baker;Cancer Res.,1990
5. Transcriptional regulation by p53;Beckerman;Cold Spring Harb. Perspect. Biol.,2010
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