Home-Based, Adaptive Cognitive Training for Cognitively Normal Older adults: Initial Efficacy Trial

Author:

Lee Hyun Kyu1,Kent James D2,Wendel Christopher3,Wolinsky Fredric D4ORCID,Foster Eric D5,Merzenich Michael M1,Voss Michelle W23

Affiliation:

1. Department of Research and Development, Posit Science Inc., San Francisco, California

2. Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa

3. Department of Psychological and Brain Sciences, University of Iowa, Iowa

4. Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa

5. Department of Biostatistics, College of Public Health, University of Iowa, Iowa

Abstract

Abstract Objectives We examined whether a home-based, adaptive cognitive training (CT) program would lead to cognitive performance changes on a neuropsychological test battery in cognitively normal older adults. Method Sixty-eight older adults (age = 70.0, SD = 3.74) were randomly assigned to either CT or an active control group (AC, casual computer games). Participants were instructed to train on their assigned programs for 42 min per day, 5 days per week, over 10 weeks (35 hr of total program usage). Participants completed tests of processing speed, working memory, and executive control before and after 10 weeks of training. Results Training groups did not differ in performance before training. After training, CT participants out-performed AC participants in the overall cognitive composite score, driven by processing speed and working memory domains. Discussion Our results show that a limited dose of home-based CT can drive cognitive improvements as measured with neuropsychological test battery, suggesting potential cognitive health maintenance implications for cognitively normal older adults.

Funder

National Institutes of Health

National Institute on Aging

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Gerontology,Clinical Psychology,Social Psychology

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