Identification of metabolically stable 5′-phosphate analogs that support single-stranded siRNA activity-Reference-Cited by-同舟云学术

Identification of metabolically stable 5′-phosphate analogs that support single-stranded siRNA activity

Published:2015-03-09 Issue:6 Volume:43 Page:2993-3011
ISSN:1362-4962
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Prakash Thazha P.,Lima Walt F.,Murray Heather M.,Li Wenyu,Kinberger Garth A.,Chappell Alfred E.,Gaus Hans,Seth Punit P.,Bhat Balkrishen,Crooke Stanley T.,Swayze Eric E.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/43/6/2993/17434894/gkv162.pdf

Reference40 articles.

1. RNA interference is mediated by 21- and 22-nucleotide RNAs;Elbashir;Genes Dev.,2001

2. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells;Elbashir;Nature,2001

3. RNAi in clinical studies;Kubowicz;Curr. Med. Chem.,2013

4. A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus;DeVincenzo;Proc. Natl. Acad. Sci. U.S.A.,2010

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