Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

Published:2011-06-01 Issue:1 Volume:92 Page:85-94
ISSN:1755-3245
Container-title:Cardiovascular Research
language:en
Short-container-title:

Author:

Yan Ling¹²,Wei Xiang³,Tang Qi-Zhu¹²,Feng Jinghua¹²,Zhang Yan¹²,Liu Chen⁴,Bian Zhou-Yan¹²,Zhang Lian-Feng⁵,Chen Manyin⁶,Bai Xue¹²,Wang Ai-Bing⁷,Fassett John⁸,Chen Yingjie⁸,He You-Wen⁹,Yang Qinglin¹⁰,Liu Peter P.¹¹,Li Hongliang¹²

Affiliation:

1. Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

2. Cardiovascular Research Institute of Wuhan University, Wuhan 430060, China

3. Department of Thoracic and Cardiac Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

4. Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China

5. Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Beijing, China

6. Division of Cardiology, Heart and Stroke/Richard Lewar Centre of Excellence, University Health Network, University of Toronto, Toronto, ON, CanadaM5S3E2

7. Laboratory of Molecular Cardiology, NHLBI, National Institutes of Health, Bethesda, MD 20892-1762, USA

8. Cardiovascular Division, University of Minnesota, Minneapolis, MN 55455, USA

9. Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA

10. Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360, USA

11. Department of Cardiology, Toronto General Hospital, Toronto, ON, CanadaM5G2C4

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

http://academic.oup.com/cardiovascres/article-pdf/92/1/85/25229310/cvr159.pdf

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4. The extracellular matrix and the cytoskeleton in heart hypertrophy and failure;Jane-Lise;Heart Fail Rev,2000

5. Integrin signaling;Giancotti;Science.,1999

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