Previous Dengue Infection and Mortality in Coronavirus Disease 2019 (COVID-19)

Author:

Silvestre Odilson M1,Costa Letícia R1,Lopes Bianca V R1,Barbosa Mariana R1,Botelho Kárenn K P1,Albuquerque Kelvyn L C1,Souza Anna G S1,Coelho Lorran A1,de Oliveira Anderson J1,Barantini Cínthia B1,Neves Sebastião A V M1,Nadruz Wilson2,Maguire James H3,Fernandes-Silva Miguel M4

Affiliation:

1. Federal University of Acre, Rio Branco, Brazil

2. University of Campinas, Campinas, Brazil

3. Division of Infectious Disease, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

4. Federal University of Parana, Curitiba, Brazil

Abstract

Abstract We studied 2351 participants with coronavirus disease 2019; 1177 (50%) reported previous dengue infection. Those without previous dengue had a higher risk of death (hazard ratio: .44; 95% confidence interval: .22–.89; P = .023) in 60-day follow-up. These findings raise the possibility that dengue might induce immunological protection against severe acute respiratory syndrome coronavirus 2.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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