Infant Hospitalizations and Fatalities Averted by the Maternal Pertussis Vaccination Program in England, 2012–2017: Post-implementation Economic Evaluation

Author:

Sandmann Frank12,Jit Mark12,Andrews Nick1,Buckley Hannah L3,Campbell Helen4,Ribeiro Sonia4,Sile Bersabeh4,Stowe Julia4,Tessier Elise4,Ramsay Mary4,Choi Yoon H1,Amirthalingam Gayatri4

Affiliation:

1. Statistics, Modelling, and Economics Department, National Infection Service, Public Health England, London, United Kingdom

2. Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

3. PICANet, School of Medicine, University of Leeds, Leeds, United Kingdom

4. Immunisation and Countermeasures Department, National Infection Service, Public Health England, London, United Kingdom

Abstract

Abstract In October 2012, a maternal pertussis vaccination program was implemented in England following an increased incidence and mortality in infants. We evaluated the cost-effectiveness of the program by comparing pertussis-related infant hospitalizations and deaths in 2012–2017 with nonvaccination scenarios. Despite considerable uncertainties, findings support the cost-effectiveness of the program.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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