Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington

Author:

Mani Nandita S1,Budak Jehan Z2,Lan Kristine F2,Bryson-Cahn Chloe2,Zelikoff Allison3,Barker Gwendolyn E C4,Grant Carolyn W5,Hart Kristi5,Barbee Carrie J6,Sandoval Marissa D6,Dostal Christine L6,Corcorran Maria2,Ungerleider Hal M7,Gates Jeff O8,Olin Svaya V9,Bryan Andrew10,Hoffman Noah G10,Marquis Sara R11,Harvey Michelle L12,Nasenbeny Keri13,Mertens Kathleen14,Chew Lisa D15,Greninger Alexander L1011,Jerome Keith R1011,Pottinger Paul S2,Dellit Timothy H2,Liu Catherine211,Pergam Steven A211,Neme Santiago2,Lynch John B2,Kim H Nina216,Cohen Seth A2

Affiliation:

1. Department of Medicine, School of Medicine, University of Washington, Seattle, Washington, USA

2. Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA

3. Population Health, Harborview Medical Center, Seattle, Washington, USA

4. Allied Ambulatory Care Services, Harborview Medical Center, Seattle, Washington, USA

5. Patient Care Services, University of Washington Medical Center–Northwest, Seattle, Washington, USA

6. Harborview Medical Center, Seattle, Washington, USA

7. Respiratory Therapy, University of Washington Medical Center–Northwest, Seattle, Washington, USA

8. Employee Health, University of Washington Medical Center–Northwest, Seattle, Washington, USA

9. Infection Prevention and Control, University of Washington Medical Center–Northwest, Seattle, Washington, USA

10. Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA

11. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

12. Clinical Trials Office, University of Washington, Seattle, Washington, USA

13. Patient Care Services, University of Washington Medical Center, Seattle, Washington, USA

14. Primary Care and Population Health, Harborview Medical Center, Seattle, Washington, USA

15. Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA

16. Allergy and Infectious Diseases/Department of Medicine Research Collaboratory, University of Washington, Seattle, Washington, USA

Abstract

Abstract Background Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States. Methods We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19. Results Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered. Conclusions During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff. Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2–negative employees to work.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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