Long COVID in the Faroe Islands: A Longitudinal Study Among Nonhospitalized Patients

Author:

Petersen Maria Skaalum12ORCID,Kristiansen Marnar Fríðheim134,Hanusson Katrin Dahl2,Danielsen Marjun Eivindardóttir24,á Steig Bjarni34,Gaini Shahin356,Strøm Marin17,Weihe Pál12

Affiliation:

1. Centre of Health Sciences, Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands

2. Department of Occupational Medicine and Public Health, The Faroese Hospital System, Tórshavn, Faroe Islands

3. Medical Department, National Hospital of the Faroe Islands, Tórshavn, Faroe Islands

4. COVID-19 Task Force, Ministry of Health, Faroe Islands

5. Department of Infectious Diseases, Odense University Hospital, Odense, Denmark

6. Department of Clinical Research, University of Southern Denmark, Odense, Denmark

7. Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark

Abstract

Abstract Background Little is known about long-term recovery from coronavirus disease 2019 (COVID-19) disease, especially in nonhospitalized individuals. In this longitudinal study we present symptoms registered during the acute phase as well as long COVID (ie, long-lasting COVID-19 symptoms) in patients from the Faroe Islands. Methods All consecutive patients with confirmed reverse transcription–polymerase chain reaction testing from April to June 2020 were invited to participate in this study for the assessment of long COVID. Demographic and clinical characteristics and self-reported acute and persistent symptoms were assessed using a standardized detailed questionnaire administered at enrollment and at repeated phone interviews in the period 22 April to 16 August. Results Of the 180 participants (96.3% of the 187 eligible COVID-19 patients), 53.1% reported persistence of at least 1 symptom after a mean of 125 days after symptoms onset, 33.0% reported 1 or 2 symptoms, and 20.1% reported 3 or more symptoms. At the last follow-up, 46.9% were asymptomatic compared with 4.4% during the acute phase. The most prevalent persistent symptoms were fatigue, loss of smell and taste, and arthralgias. Conclusions Our results show that it might take months for symptoms to resolve, even among nonhospitalized persons with mild illness course in the acute phase. Continued monitoring for long COVID is needed.

Funder

Cooperation’s p/f Krúnborg and Bortartún

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference13 articles.

1. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review;Wiersinga;JAMA,2020

2. The new challenge of geriatrics: saving frail older people from the SARS-COV-2 pandemic infection;Landi;J Nutr Health Aging,2020

3. Long COVID: let patients help define long-lasting COVID symptoms;Nature,2020

4. Persistent symptoms in patients after acute COVID-19;Carfì;JAMA,2020

5. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study;Xiong;Clin Microbiol Infect,2020

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