Highlights of the 12th International Bordetella Symposium

Author:

Locht Camille1,Carbonetti Nicholas H2,Cherry James D3,Damron F Heath45,Edwards Kathryn M6,Fernandez Rachel7,Harvill Eric T8,Hozbor Daniela9,Mills Kingston H G10,Rodriguez Maria Eugenia11,Mascart Françoise12

Affiliation:

1. Université Lille, Centre National de la Recherche Scientifique, Inserm, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1019, Unité Mixte de Recherche 8204, Center for Infection and Immunity of Lille, Lille, France

2. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

3. David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA

4. Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, West Virginia, USA

5. Vaccine Development Center at West Virginia University Health Science Center, West Virginia University, Morgantown, West Virginia, USA

6. Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

7. Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada

8. Department of Infectious Diseases, College of Veterinary Sciences, University of Georgia, Athens, Georgia, USA

9. Laboratorio VacSal, Instituto de Biotecnología y Biología Molecular, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Cientificas y Técnicas, La Plata, Argentina

10. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

11. Centro de Investigacion y Desarrollo en Fermentaciones Industriales, Consejo Nacional de Investigaciones Cientificas y Técnicas, La Plata, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

12. Laboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxelles, Brussels, Belgium

Abstract

Abstract To commemorate the 100th anniversary of the Nobel prize being awarded to Jules Bordet, the discoverer of Bordetella pertussis, the 12th International Bordetella Symposium was held from 9 to 12 April 2019 at the Université Libre de Bruxelles, where Jules Bordet studied and was Professor of Microbiology. The symposium attracted more than 300 Bordetella experts from 34 countries. They discussed the latest epidemiologic data and clinical aspects of pertussis, Bordetella biology and pathogenesis, immunology and vaccine development, and genomics and evolution. Advanced technological and methodological tools provided novel insights into the genomic diversity of Bordetella and a better understanding of pertussis disease and vaccine performance. New molecular approaches revealed previously unrecognized complexity of virulence gene regulation. Innovative insights into the immune responses to infection by Bordetella resulted in the development of new vaccine candidates. Such discoveries will aid in the design of more effective approaches to control pertussis and other Bordetella-related diseases.

Funder

Université de Lille

National Institute of Allergy and Infectious Diseases

Food and Drug Administration

Sanofi Pasteur; ILiAD Biotechnologies

GlaxoSmithKline

BioNet; and the Microbiology Society

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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