Evaluation of the Accuracy of 99DOTS, a Novel Cellphone-based Strategy for Monitoring Adherence to Tuberculosis Medications: Comparison of DigitalAdherence Data With Urine Isoniazid Testing-Reference-Cited by-同舟云学术

Evaluation of the Accuracy of 99DOTS, a Novel Cellphone-based Strategy for Monitoring Adherence to Tuberculosis Medications: Comparison of DigitalAdherence Data With Urine Isoniazid Testing

Published:2020-03-28 Issue:9 Volume:71 Page:e513-e516
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Thomas Beena E¹,Kumar J Vignesh¹,Chiranjeevi M¹,Shah Daksha²,Khandewale Amit¹,Thiruvengadam Kannan¹,Haberer Jessica E³,Mayer Kenneth H⁴⁵,Subbaraman Ramnath⁶⁷^ORCID

Affiliation:

1. Department of Social and Behavioural Research, National Institute for Research in Tuberculosis, Chennai, India

2. Public Health Department, Municipal Corporation of Greater Mumbai, Mumbai, India

3. Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, USA

4. The Fenway Institute, Fenway Health, Boston, Massachusetts, USA

5. Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

6. Department of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USA

7. Division of Geographic Medicine and Infectious Diseases, Tufts University School of Medicine, Boston, Massachusetts, USA

Abstract

Abstract 99DOTS is a cellphone-based strategy for monitoring tuberculosis medication adherence. In a sample of 597 Indian patients with tuberculosis, we compared 99DOTS’ adherence assessments against results of urine isoniazid tests collected during unannounced home visits. 99DOTS had suboptimal accuracy for measuring adherence, partly due to poor patient engagement with 99DOTS.

Funder

Bill and Melinda Gates Foundation

Harvard Catalyst KL2/Catalyst Medical Investigator Training

Harvard Center for AIDS Research

Doris Duke Clinical Scientist Development Award

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa333/33215745/ciaa333.pdf