Early Insights From Clinical Trials of Typhoid Conjugate Vaccine-Reference-Cited by-同舟云学术

Early Insights From Clinical Trials of Typhoid Conjugate Vaccine

Published:2020-07-29 Issue:Supplement_2 Volume:71 Page:S155-S159
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Neuzil Kathleen M¹,Basnyat Buddha²,Clemens John D³,Gordon Melita A⁴⁵,Patel Priyanka D⁴,Pollard Andrew J⁶⁷,Shakya Mila²,Qadri Firdausi³

Affiliation:

1. University of Maryland School of Medicine, Baltimore, Maryland, USA

2. Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal

3. Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh

4. Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi

5. Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom

6. Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom

7. National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom

Abstract

Abstract Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introductions. Forthcoming trial data will continue to inform programmatic use of typhoid conjugate vaccine.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/article-pdf/71/Supplement_2/S155/33546454/ciaa370.pdf

Reference22 articles.

1. The role of public health improvements in health advances: the twentieth-century United States;Cutler;Demography,2005

2. The burden of typhoid fever in low- and middle-income countries: a meta-regression approach;Antillón;PLoS Negl Trop Dis,2017

3. Changes in historical typhoid transmission across 16 U.S. cities, 1889–1931: quantifying the impact of investments in water and sewer infrastructures;Phillips;PLoS Negl Trop Dis,2020

4. Burden of typhoid fever in low-income and middle-income countries: a systematic, literature-based update with risk-factor adjustment;Mogasale;Lancet Glob Health,2014

5. The global burden of typhoid fever;Crump;Bull World Health,2004

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficacy of typhoid conjugate vaccine in Malawian children – Authors’ reply;The Lancet;2024-08

2. A phase II clinical trial of a Vi-DT typhoid conjugate vaccine in healthy Indonesian adolescents and adults: one-month evaluation of safety and immunogenicity;Tropical Diseases, Travel Medicine and Vaccines;2024-02-01

3. Typhoid Fever Vaccines;Plotkin's Vaccines;2023

4. Controlled human infectious models, a path forward in uncovering immunological correlates of protection: Lessons from enteric fevers studies;Frontiers in Microbiology;2022-09-20

5. Evaluation of Typhoid Conjugate Vaccine Effectiveness in Ghana (TyVEGHA) Using a Cluster-Randomized Controlled Phase IV Trial: Trial Design and Population Baseline Characteristics;Vaccines;2021-03-19