Prolonged Maternal Shedding and Maternal-fetal Transmission of Measles Virus

Author:

Charlier Caroline123ORCID,Dina Julia45,Freymuth François45,Vabret Astrid45,Lortholary Olivier3,Antona Denise6,Lecuit Marc123

Affiliation:

1. Institut Pasteur, Biology of Infection Unit, Paris, France

2. Inserm U1117, Paris, France

3. Université de Paris, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Institut Imagine, Paris, France

4. Normandie University, University of Caen Normandy, Groupe de recherche sur l’adaptation microbienne EA2656, Centre Hospitalier Universitaire de Caen, Virology Department, Caen, France

5. National Reference Center for Measles Mumps and Rubella, Centre Hospitalier Universitaire de Caen, Caen, France

6. Santé Publique France, Saint Maurice, France

Abstract

Abstract Prolonged measles virus detection in maternal saliva and blood was evidenced in 6 pregnant women. Maternal-fetal transmission was evidenced in 2 of 4 infants who were asymptomatic at birth, 21–24 weeks after maternal infection. Whereas peripartum congenital measles is severe, asymptomatic measles virus vertical transmission can occur earlier in pregnancy.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference16 articles.

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2. Maternal, fetal, and neonatal outcomes associated with measles during pregnancy: Namibia, 2009–2010;Ogbuanu;Clin Infect Dis,2014

3. Measles in pregnancy: a descriptive study of 58 cases;Eberhart-Phillips;Obstet Gynecol,1993

4. Complications of measles during pregnancy;Atmar;Clin Infect Dis,1992

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1. Varicella, measles, and mumps;Remington and Klein's Infectious Diseases of the Fetus and Newborn Infant;2025

2. Viral etiology of measles‐like rash in Guinean children during the COVID epidemic in 2022;Journal of Medical Virology;2024-02

3. Asymptomatic viruses detectable in saliva in the first year of life: a narrative review;Pediatric Research;2023-12-22

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