Powassan Virus Infection Likely Acquired Through Blood Transfusion Presenting as Encephalitis in a Kidney Transplant Recipient

Author:

Taylor Lindsay1ORCID,Condon Taryn2,Destrampe Eric M3,Brown Jennifer A2,McGavic Jeanette2,Gould Carolyn V4,Chambers Trudy V4,Kosoy Olga I4,Burkhalter Kristen L4,Annambhotla Pallavi5,Basavaraju Sridhar V5,Groves Jamel6,Osborn Rebecca A7,Weiss John8,Stramer Susan L6,Misch Elizabeth A1

Affiliation:

1. Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

2. Epidemiology Resource Center, Indiana State Department of Health, Indianapolis, Indiana, USA

3. Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

4. Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA

5. Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

6. American Red Cross Scientific Affairs, Gaithersburg, Maryland, USA

7. Division of Public Health, Wisconsin Department of Health Services, Madison, Wisconsin, USA

8. Department of Pathology and Laboratory Medicine, University of Wisconsin Hospital and Clinics, Madison, Wisconsin and American Red Cross Blood Services, Madison, Wisconsin, USA

Abstract

Abstract A kidney transplant patient without known tick exposure developed encephalitis 3 weeks after transplantation. During the transplant hospitalization, the patient had received a blood transfusion from an asymptomatic donor later discovered to have been infected with Powassan virus. Here, we describe a probable instance of transfusion-transmitted Powassan virus infection.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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