Inverse Association Between Chronic Hepatitis B Infection and Coronavirus Disease 2019 (COVID-19): Immune Exhaustion or Coincidence?

Author:

Anugwom Chimaobi M12,Aby Elizabeth S12,Debes Jose D123

Affiliation:

1. Division of Gastroenterology and Hepatology, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA

2. Division of Infectious Diseases, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA

3. Division of Gastroenterology, Hennepin Healthcare, Minneapolis, Minnesota, USA

Funder

Robert Wood Johnson Foundation’s Harold Amos Medical Faculty Development Program

National Cancer Institute

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference16 articles.

1. Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV [manuscript published online ahead of print 9 April 2020];Zhao;Clin Infect Dis,2020

2. Prevalence of hepatitis B virus infection in Shenzhen, China, 2015–2018;Tao;Sci Report,2019

3. Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infection;Crawford;Immunity,2014

4. The path to cancer and back: immune modulation during hepatitis C virus infection, progression to fibrosis and cancer, and unexpected roles of new antivirals;Debes;Transplantation,2017

5. Dynamic, helminth-induced immune modulation influences the outcome of acute and chronic hepatitis B virus infection;Loffredo-Verde;J Infect Dis,2020

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