Quantitative Trait Loci: A Meta-analysis-Reference-Cited by-同舟云学术

Quantitative Trait Loci: A Meta-analysis

Published:2000-05-01 Issue:1 Volume:155 Page:463-473
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Goffinet Bruno¹,Gerber Sophie²

Affiliation:

1. INRA, Laboratoire de Biométrie et d'Intelligence Artificielle, F-31326 Castanet-Tolosan Cedex, France

2. INP/ENSAT, Laboratoire de Biotechnologie et d'Amélioration des Plantes, F-31326 Castanet-Tolosan Cedex, France

Abstract

Abstract This article presents a method to combine QTL results from different independent analyses. This method provides a modified Akaike criterion that can be used to decide how many QTL are actually represented by the QTL detected in different experiments. This criterion is computed to choose between models with one, two, three, etc., QTL. Simulations are carried out to investigate the quality of the model obtained with this method in various situations. It appears that the method allows the length of the confidence interval of QTL location to be consistently reduced when there are only very few “actual” QTL locations. An application of the method is given using data from the maize database available online at http://www.agron.missouri.edu/.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/155/1/463/42029537/genetics0463.pdf

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