1. Department of Molecular Genetics, University of Toronto , Toronto, ON M5S 1A1, Canada
2. Donnelly Centre, University of Toronto , Toronto, ON M5S 1A1, Canada
3. Faculty of Pharmaceutical Sciences, University of British Columbia , Vancouver, BC V6T 1Z4, Canada
4. Department of Computer Science, McGill University , Montreal, QC H3A 0G4, Canada