Affiliation:
1. Department of Genetics, University of California, Berkeley, California 94720
Abstract
ABSTRACT
HLA data from the A and B loci for 22 populations were compared with the neutrality expectations from Ewens' sampling theory. In 25 of 44 cases, there was significantly less homozygosity than expected. Although a number of factors can affect homozygosity in this manner, upon close examination only symmetrical balancing selection appears to be consistent with these data.
Publisher
Oxford University Press (OUP)
Cited by
166 articles.
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