What is new in FungiDB: a web-based bioinformatics platform for omics-scale data analysis for fungal and oomycete species

Author:

Basenko Evelina Y1ORCID,Shanmugasundram Achchuthan12ORCID,Böhme Ulrike1ORCID,Starns David1ORCID,Wilkinson Paul A1ORCID,Davison Helen R1ORCID,Crouch Kathryn3ORCID,Maslen Gareth4ORCID,Harb Omar S5ORCID,Amos Beatrice6,McDowell Mary Ann7ORCID,Kissinger Jessica C8ORCID,Roos David S5ORCID,Jones Andrew1ORCID

Affiliation:

1. Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool L69 7BE , UK

2. Genomics England Limited , London E14 5AB , UK

3. School of Infection and Immunity, University of Glasgow , Glasgow G12 8QQ , UK

4. Imperial College London , London SW7 2BU , UK

5. University of Pennsylvania , Philadelphia, PA 19104 , USA

6. Wellcome Genome Campus , Hinxton CB10 1SA , UK

7. University of Notre Dame , Notre Dame, IN 46556 , USA

8. University of Georgia , Athens, GA 30602 , USA

Abstract

Abstract FungiDB (https://fungidb.org) serves as a valuable online resource that seamlessly integrates genomic and related large-scale data for a wide range of fungal and oomycete species. As an integral part of the VEuPathDB Bioinformatics Resource Center (https://veupathdb.org), FungiDB continually integrates both published and unpublished data addressing various aspects of fungal biology. Established in early 2011, the database has evolved to support 674 datasets. The datasets include over 300 genomes spanning various taxa (e.g. Ascomycota, Basidiomycota, Blastocladiomycota, Chytridiomycota, Mucoromycota, as well as Albuginales, Peronosporales, Pythiales, and Saprolegniales). In addition to genomic assemblies and annotation, over 300 extra datasets encompassing diverse information, such as expression and variation data, are also available. The resource also provides an intuitive web-based interface, facilitating comprehensive approaches to data mining and visualization. Users can test their hypotheses and navigate through omics-scale datasets using a built-in search strategy system. Moreover, FungiDB offers capabilities for private data analysis via the integrated VEuPathDB Galaxy platform. FungiDB also permits genome improvements by capturing expert knowledge through the User Comments system and the Apollo genome annotation editor for structural and functional gene curation. FungiDB facilitates data exploration and analysis and contributes to advancing research efforts by capturing expert knowledge for fungal and oomycete species.

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Department of Health and Human Services

Wellcome Trust

University of Liverpool

Publisher

Oxford University Press (OUP)

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