THE DNA OF CAENORHABDITIS ELEGANS

Author:

Sulston J E1,Brenner S1

Affiliation:

1. Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 ZQH, England

Abstract

ABSTRACT Chemical analysis and a study of renaturation kinetics show that the nematode, Caenorhabditis elegans, has a haploid DNA content of 8 x IO7 base pairs (20 times the genome of E. coli). Eighty-three percent of the DNA sequences are unique. The mean base composition is 36% GC; a small component, containing the rRNA cistrons, has a base composition of 51% GC. The haploid genome contains about 300 genes for 4s RNA, 110 for 5s RNA, and 55 for (18 + 28)S RNA.

Publisher

Oxford University Press (OUP)

Subject

Genetics

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