1. Michael Smith Laboratories, Department of Medical Genetics, University of British Columbia, Vancouver , BC , Canada
2. The Donnelly Centre and Department of Molecular Genetics, University of Toronto , Toronto, ON M5S 3E1 , Canada
3. Department of Genome Sciences and Department of Bioengineering, University of Washington , Seattle, WA , USA
4. Departments of Molecular and Human Genetics, and Neuroscience Neurological Research Institute, Texas Children's Hospital Baylor College of Medicine, Houston, TX, USA