Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistantStaphylococcus aureusCoinfection in Children With Influenza-related Critical Illness

Author:

Randolph Adrienne G123ORCID,Xu Ruifei1,Novak Tanya1,Newhams Margaret M1,Bubeck Wardenburg Juliane4,Weiss Scott L5,Sanders Ronald C6,Thomas Neal J7,Hall Mark W8,Tarquinio Keiko M9,Cvijanovich Natalie10,Gedeit Rainer G11,Truemper Edward J12,Markovitz Barry13,Hartman Mary E4,Ackerman Kate G14,Giuliano John S15,Shein Steven L16,Moffitt Kristin L317,Kong Michele,Sanders Ronald C,Hefley Glenda,Tellez David,Typpo Katri,Markovitz Barry,Morzov Rica Sharon P,Graciano Ana Lia,Cvijanovich Natalie,Flori Heidi,Brumfield Becky,Anas Nick,Schwarz Adam,Vargas-Shiraishi Ofelia,McQuillen Patrick,Sapru Anil,Mourani Peter,Czaja Angela,Carroll Christopher,Giuliano John S,Tala Joana,Palmieri Lisa,McLaughlin Gwenn,Paden Matthew,Tarquinio Keiko,Stone Cheryl L,Coates Bria M,Pinto Neethi,Sullivan Janice,Montgomery Vicki,Randolph Adrienne G,Xu Ruifei,Agan Anna A,Novak Tanya,Newhams Margaret M,Bembea Melania,Kudchadkar Sapna,Kurachek Stephen C,Hartman Mary E,Doctor Allan,Barrale Tina,Truemper Edward J,Mahapatra Sidharth,Dawson Machelle,Kustka Lucinda,Malone Kristin,Schrack Melanie,Katyal Chhavi,Ackerman Kate G,Daugherty L Eugene,Shein Steven L,Lemon Eloise,DeFrancesco Kathryn,Hall Mark W,Steele Lisa,Thomas Neal,Spear Debra,Weiss Scott L,Fitzgerald Julie,Bush Jenny L,Graham Kathryn,Barr Frederick E,Higgerson Renee,Christie LeeAnn,Bowens Cindy Darnell,Thompson Marita,Loftis Laura L,Jaimon Nancy,Wilson Douglas F,Gedeit Rainer G,Murkowski Kathy,Siegel Katherine,Dugas Marc-André,

Affiliation:

1. Department of Anesthesia, Critical Care, and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts

2. Department of Anesthesia, Harvard Medical School, Boston, Massachusetts

3. Department of Pediatrics, Harvard Medical School, Boston, Massachusetts

4. Department of Pediatrics, St. Louis Children’s Hospital, Missouri

5. Department of Pediatrics, Children’s Hospital of Philadelphia, Pennsylvania

6. Section of Pediatric Critical Care, Department of Pediatrics, Arkansas Children’s Hospital, Little Rock

7. Division of Pediatric Critical Care Medicine, Penn State Hershey Children’s Hospital, Pennsylvania

8. Department of Pediatrics, Nationwide Children’s Hospital, Columbus, Ohio

9. Division of Critical Care Medicine, Children’s Healthcare of Atlanta at Egleston, Emory University School of Medicine, Georgia

10. Department of Critical Care Medicine, University of California–San Francisco, Benioff Children’s Hospital Oakland

11. Department of Pediatrics, Children’s Hospital of Wisconsin, Milwaukee

12. Department of Pediatrics, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska

13. Department of Anesthesiology Critical Care Medicine, Children’s Hospital Los Angeles, California

14. Department of Pediatrics, Golisano Children’s Hospital, Rochester, New York

15. Department of Pediatrics, Yale–New Haven Children’s Hospital, Connecticut

16. Division of Pediatric Critical Care Medicine, Rainbow Babies and Children’s Hospital, Cleveland, Ohio

17. Division of Infectious Diseases, Department of Medicine, Boston Children’s Hospital, Massachusetts

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Centers for Disease Control and Prevention

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference39 articles.

1. Infection with community-onset Staphylococcus aureus and influenza virus in hospitalized children;Reed;Pediatr Infect Dis J,2009

2. Severe methicillin-resistant Staphylococcus aureus community-acquired pneumonia associated with influenza—Louisiana and Georgia, December 2006-January 2007;Centers for Disease Control and Prevention;MMWR Morb Mortal Wkly Rep,2007

3. Influenza-associated pediatric mortality in the United States: increase of Staphylococcus aureus coinfection;Finelli;Pediatrics,2008

4. Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States;Rice;Crit Care Med,2012

5. Critically ill children during the 2009–2010 influenza pandemic in the United States;Randolph;Pediatrics,2011

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