The Effect of Menopausal Status, Age, and Human Immunodeficiency Virus (HIV) on Non-AIDS Comorbidity Burden Among US Women

Author:

Collins Lauren F12ORCID,Mehta C Christina1,Palella Frank J3,Fatade Yetunde4,Naggie Susanna5,Golub Elizabeth T6,Anastos Kathryn7,French Audrey L8,Kassaye Seble9,Taylor Tonya N10,Fischl Margaret A11,Adimora Adaora A12,Kempf Mirjam-Colette13,Tien Phyllis C1415,Sheth Anandi N12,Ofotokun Ighovwerha12

Affiliation:

1. Division of Infectious Diseases, Emory University School of Medicine , Atlanta, Georgia , USA

2. Grady Healthcare System, Infectious Diseases Program , Atlanta, Georgia , USA

3. Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University , Chicago, Illinois , USA

4. Department of Medicine, Emory University School of Medicine , Atlanta, Georgia , USA

5. Duke Clinical Research Institute and Duke University School of Medicine , Durham, North Carolina , USA

6. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland , USA

7. Department of Medicine, Albert Einstein College of Medicine , Bronx, New York , USA

8. Division of Infectious Diseases, CORE Center, Stroger Hospital of Cook County , Chicago, Illinois , USA

9. Georgetown University Medical Center , Washington, DC , USA

10. SUNY Downstate Health Sciences University , Brooklyn, New York , USA

11. Division of Infectious Diseases, University of Miami Miller School of Medicine , Miami, Florida , USA

12. School of Medicine and UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina , USA

13. Schools of Nursing, Public Health, and Medicine, University of Alabama at Birmingham , Birmingham, Alabama , USA

14. Division of Infectious Diseases, Department of Medicine, University of California, San Francisco , San Francisco, California , USA

15. Medical Service, Department of Veterans Affairs , San Francisco, California , USA

Abstract

Abstract Menopause may impact the earlier onset of aging-related comorbidities among women with versus without human immunodeficiency virus (HIV). We found that menopausal status, age, and HIV were independently associated with higher comorbidity burden, and that HIV impacted burden most in the pre-/perimenopausal phases.

Funder

Atlanta Clinical Research Site

Baltimore CRS

Bronx CRS

Brooklyn CRS

Data Analysis and Coordination Center

Chicago-Cook County CRS

Chicago-Northwestern CRS

Northern California CRS

Los Angeles CRS

Metropolitan Washington CRS

Miami CRS

Pittsburgh CRS

UNC CRS

National Heart, Lung, and Blood Institute

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Human Genome Research Institute

National Institute on Aging

National Institute of Dental and Craniofacial Research

National Institute of Allergy and Infectious Diseases

National Institute of Neurological Disorders and Stroke

National Institute of Mental Health

National Institute on Drug Abuse

National Institute of Nursing Research

National Cancer Institute

National Institute on Alcohol Abuse and Alcoholism

National Institute on Deafness and Other Communication Disorders

National Institute of Diabetes and Digestive and Kidney Diseases

MWCCS data collection

Emory Specialized Center of Research Excellence

National Center for Advancing Translational Sciences

National Institutes of Health

Emory School of Medicine

Doris Duke Charitable Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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