Hepatitis B Virus (HBV) Replication During Tenofovir Therapy Is Frequent in Human Immunodeficiency Virus/HBV Coinfection-Reference-Cited by-同舟云学术

Hepatitis B Virus (HBV) Replication During Tenofovir Therapy Is Frequent in Human Immunodeficiency Virus/HBV Coinfection

Published:2022-10-15 Issue:4 Volume:76 Page:730-733
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Hofmann Eveline¹^ORCID,Surial Bernard¹,Boillat-Blanco Noémie²,Günthard Huldrych F³⁴,Stöckle Marcel⁵,Bernasconi Enos⁶,Schmid Patrick⁷,Calmy Alexandra⁸,Suter-Riniker Franziska⁹,Rauch Andri¹,Wandeler Gilles¹¹⁰,Béguelin Charles¹,Abela I,Aebi-Popp K,Anagnostopoulos A,Battegay M,Bernasconi E,Braun DL,Bucher HC,Calmy A,Cavassini M,Ciuffi A,Dollenmaier G,Egger M,Elzi L,Fehr J,Fellay J,Furrer H,Fux CA,Günthard HF,Hachfeld A,Haerry D,Hasse B,Hirsch HH,Hoffmann M,Hösli I,Huber M,Kahlert CR,Kaiser L,Keiser O,Klimkait T,Kouyos RD,Kovari H,Kusejko K,Martinetti G,Martinez de Tejada B,Marzolini C,Metzner KJ,Müller N,Nemeth J,Nicca D,Paioni P,Pantaleo G,Perreau M,Rauch A,Schmid P,Speck R,Stöckle M,Tarr P,Trkola A,Wandeler G,Yerly S,

Affiliation:

1. Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern , Bern , Switzerland

2. Service of Infectious Diseases, Lausanne University Hospital and University of Lausanne , Lausanne , Switzerland

3. Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich , Zurich , Switzerland

4. Institute of Medical Virology, University of Zurich , Zurich , Switzerland

5. Department of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel , Basel , Switzerland

6. Division of Infectious Diseases, Regional Hospital of Lugano , Lugano , Switzerland

7. Division of Infectious Diseases, Cantonal Hospital of St. Gallen , St. Gallen , Switzerland

8. Division of Infectious Diseases, Geneva University Hospital, University of Geneva , Geneva , Switzerland

9. Institute for Infectious Diseases, University of Bern , Switzerland

10. Institute of Social and Preventive Medicine, University of Bern , Bern , Switzerland

Abstract

AbstractIn the Swiss HIV Cohort Study, 61 of 222 (27%) HIV–suppressed persons with chronic hepatitis B virus (HBV) infection had HBV replication after 2 years on tenofovir, of whom 77% were suppressed thereafter. Self-reported adherence to therapy and HBV viral load at tenofovir initiation were predictors of persistent replication.

Funder

Swiss National Science Foundation

NEAT-ID Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciac823/47954109/ciac823.pdf

Reference15 articles.

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2. Suppression of HBV by tenofovir in HBV/HIV coinfected patients: a systematic review and meta-analysis;Price;PLoS One,2013