1. Kaohsiung Municipal Ta-Tung Hospital , Kaohsiung , Taiwan
2. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital , Kaohsiung , Taiwan
3. Department of Internal Medicine, Kaohsiung Medical University Hospital , Kaohsiung , Taiwan
4. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung , Taiwan
5. Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
6. Department of Biological Science and Technology, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
7. Center for Intelligent Drug Systems and Smart Biodevices, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
8. Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine , Taipei , Taiwan