Welder’s Anthrax: A Tale of 2 Cases

Author:

Hendricks Katherine1,Martines Roosecelis Brasil1,Bielamowicz Hannah2,Boyer Anne E3,Long Stephen4,Byers Paul5,Stoddard Robyn A1,Taylor Kathryn5,Kolton Cari Beesley1,Gallegos-Candela Maribel3,Roberts Christine5,DeLeon-Carnes Marlene1,Salzer Johanna6,Dawson Patrick7,Brown Dannette8,Templeton-LeBouf Lindsey4,Maves Ryan C9,Gulvik Chris1,Lonsway David10,Barr John R3,Bower William A1ORCID,Hoffmaster Alex1

Affiliation:

1. Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

2. Pathology Department, Fort Bend County Medical Examiner Office , Rosenberg, Texas , USA

3. Division of Laboratory Sciences, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

4. Houston Laboratory Response Network, Houston Health Department , Houston, Texas , USA

5. Office of Communicable Diseases, Mississippi State Department of Health , Jackson, Mississippi , USA

6. Division of Vector-Borne Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

7. Office of Science, Centers for Disease Control and Prevention , Atlanta , Georgia , USA

8. King Daughters Medical Center , Brookhaven, Mississippi , USA

9. Departments of Infectious Diseases and Anesthesiology, Wake Forest University School of Medicine , Winston-Salem, North Carolina , USA

10. Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

Abstract

Abstract Bacillus anthracis has traditionally been considered the etiologic agent of anthrax. However, anthrax-like illness has been documented in welders and other metal workers infected with Bacillus cereus group spp. harboring pXO1 virulence genes that produce anthrax toxins. We present 2 recent cases of severe pneumonia in welders with B. cereus group infections and discuss potential risk factors for infection and treatment options, including antitoxin.

Funder

NIH

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference53 articles.

1. Anthrax pathogenesis;Moayeri;Annu Rev Microbiol,2015

2. Systematic review: a century of inhalational anthrax cases from 1900 to 2005;Holty;Ann Intern Med,2006

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