Adverse Events Associated With Treatment for Pan-Susceptible Tuberculosis in San Francisco-Reference-Cited by-同舟云学术

Adverse Events Associated With Treatment for Pan-Susceptible Tuberculosis in San Francisco

Published:2022-11-02 Issue:6 Volume:76 Page:1121-1124
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Louie Janice K¹²,Keh Chris²,Agraz-Lara Rocio¹,Phillips Allison¹,Graves Susannah¹

Affiliation:

1. Division of Population Health, San Francisco Department of Public Health , San Francisco, California , USA

2. Department of Medicine, University of California–San Francisco , San Francisco, California , USA

Abstract

Abstract Of 373 patients treated for drug-susceptible tuberculosis, 35.4% (46.2% aged ≥65 years) developed moderate/severe adverse events that required treatment interruption (34.8%), first-line drug discontinuation (26.2%, primarily pyrazinamide), second-line drug initiation (30.0%), and treatment duration up to 3.8 months longer. More safe and effective options are needed, including for the elderly.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciac867/47465664/ciac867.pdf

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3. Tuberculosis in older adults: Seattle and King County, Washington;Toren;Clin Infect Dis,2020

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