Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Variants Using Traveler-based Genomic Surveillance at 4 US Airports, September 2021

Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Variants Using Traveler-based Genomic Surveillance at 4 US Airports, September 2021–January 2022

Published:2022-07-06 Issue:3 Volume:76 Page:e540-e543
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Wegrzyn Renee D¹,Appiah Grace D²,Morfino Robert¹,Milford Scott R³,Walker Allison Taylor²,Ernst Ezra T³,Darrow William W³,Li Siyao Lisa¹,Robison Keith¹,MacCannell Duncan⁴,Dai Dongjuan¹,Girinathan Brintha P¹,Hicks Allison L¹,Cosca Bryan¹,Woronoff Gabrielle¹,Plocik Alex M¹,Simen Birgitte B¹,Moriarty Leah²,Guagliardo Sarah Anne J²,Cetron Martin S²,Friedman Cindy R²

Affiliation:

1. Ginkgo Bioworks, Inc , Boston, Massachusetts , USA

2. Division of Global Migration and Quarantine, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

3. XpresCheck™, XpresSpa™ , New York, NY , USA

4. Office of Advanced Molecular Detection, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

Abstract

Abstract We enrolled arriving international air travelers in a severe acute respiratory syndrome coronavirus 2 genomic surveillance program. We used molecular testing of pooled nasal swabs and sequenced positive samples for sublineage. Traveler-based surveillance provided early-warning variant detection, reporting the first US Omicron BA.2 and BA.3 in North America.

Funder

CDC

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciac461/44478185/ciac461.pdf

Reference12 articles.

1. SARS-CoV-2 B. 1.1. 529 (Omicron) variant—United States, 1–8 December 2021;Centers for Disease Control and Prevention COVID-19 Response Team;MMWR Morb Mortal Wkly Rep,2021

2. Genomic surveillance for SARS-CoV-2 variants: predominance of the Delta (B. 1.617. 2) and Omicron (B. 1.1. 529) variants—United States, June 2021–January 2022;Lambrou;MMWR Morb Mortal Wkly Rep,2022

3. Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore;Tyson;bioRxiv,2020

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