Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia-Reference-Cited by-同舟云学术

Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia

Published:2016-01-10 Issue:6 Volume:25 Page:1233-1246
ISSN:0964-6906
Container-title:Human Molecular Genetics
language:en
Short-container-title:Hum. Mol. Genet.

Author:

Angarica Vladimir Espinosa,Orozco Modesto,Sancho Javier

Funder

Banco Santander Central

Hispano

Fundación Carolina

Universidad de Zaragoza

Ministerio de Economía y Competitividad

Grups de Recerca Consolidats, Generalitat de Catalunya

ISCIII

Ministerio de Ciencia e Innovación

Gobierno de Aragón

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/25/6/1233/18527743/ddw004.pdf

Reference92 articles.

1. Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis;Go;Yale J. Biol. Med.,2012

2. Versatility in ligand recognition by LDL receptor family proteins: advances and frontiers

3. The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

4. The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

5. The Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand Release

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Adsorption of Low Density Lipoproteins on an Azobenzene-Containing Polymer Brush: Modelling by Coarse-Grained Molecular Dynamics;Processes;2023-10-04

2. The computational approach to variant interpretation;Clinical DNA Variant Interpretation;2021

3. Molecular dynamics simulations for genetic interpretation in protein coding regions: where we are, where to go and when;Briefings in Bioinformatics;2019-12-08

4. Molecular modeling of LDLR aids interpretation of genomic variants;Journal of Molecular Medicine;2019-02-18

5. Screening of common genetic variants in the APOB gene related to familial hypercholesterolemia in a Saudi population;Medicine;2019-01