Chemopreventive Effects of Deguelin, a Novel Akt Inhibitor, on Tobacco-Induced Lung Tumorigenesis

Author:

Lee Ho-Young,Oh Seung-Hyun,Woo Jong K.,Kim Woo-Young,Van Pelt Carolyn S.,Price Roger E.,Cody Dianna,Tran Hai,Pezzuto John M.,Moriarty Robert M.,Hong Waun Ki

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference36 articles.

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3. Richardson CM, Sharma RA, Cox G, O'Byrne KJ. Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy. Lung Cancer2003 ; 39 : 1 –13.

4. Rusch V, Klimstra D, Venkatraman E, Pisters PW, Langenfeld J, Dmitrovsky E. Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression. Clin Cancer Res1997 ; 3 : 515 –22.

5. Fontanini G, De Laurentiis M, Vignati S, Chine S, Lucchi M, Silvestri V, et al. Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival. Clin Cancer Res1998 ; 4 : 241 –9.

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