The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination

Author:

Sakai Eiko,Bottaro Andrea,Alt Frederick W.

Publisher

Oxford University Press (OUP)

Subject

Immunology,General Medicine,Immunology and Allergy

Reference46 articles.

1. Zhang, J., Alt, F. W. and Honjo, T. 1995. Regulation of class switch recombination of the immunoglobulin heavy chain genes. In Honjo, T. and Alt, F. W., eds, Immunoglobulin Genes, 2nd edn, p. 235. Academic Press, London.

2. Lansford, R., Okada, A., Chen, J., Oltz, E., Blackwell, T., Alt, F. and Rathburn, G. 1996. Mechanism and control of immunoglobulin gene rearrangement. In Hames, B. D. and Glover, D. M., eds, Molecular Immunology, 2nd edn, p. 248. Oxford University Press, Oxford.

3. Stavnezer, J. 1996. Immunoglobulin class switching. Curr. Opin. Immunol.8:199.

4. Bottaro, A. and Alt, F. W. 1997. Local and general control elements of immunoglobulin class switching. In Vercelli, D., eds, IgE Regulation: Molecular Mechanism, p. 155. Wiley, Chichester.

5. Seidl, J. K., Bottaro, A., Vo, A., Zhang, J., Davidson, L. and Alt, F. W. 1998. An expressed neor cassette provides required functions of the Ig2b exon for class switching. Int. Immunol.10:1683.

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