The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells
Author:
Publisher
Oxford University Press (OUP)
Subject
Immunology,General Medicine,Immunology and Allergy
Link
http://academic.oup.com/intimm/article-pdf/12/7/1085/18319972/1085.pdf
Reference22 articles.
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2. Storb, U. 1996. The molecular basis of somatic hypermutation of immunoglobulin genes. Curr. Opin. Immunol.8:206.
3. Betz, A., Milstein, C., Gonzalez-Fernandes, R., Pannell, R., Larson, T. and Neuberger, M. 1994. Elements regulating somatic hypermutation of an immunoglobulin K gene: critical role for the intron enhancer/matrix attachment region. Cell77:239.
4. Tumas-Brundage, K. and Manser, T. 1997. The transcriptional promoter regulates hypermutation of the antibody heavy chain locus. J. Exp. Med.185:239.
5. Rabbits, T., Forster, A., Hamlyn, P. and Baer, R. 1984. Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma. Nature309:592.
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