A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages-Reference-Cited by-同舟云学术

A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages

Published:2018-03-07 Issue:6 Volume:67 Page:817-826
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Tripura Rupam¹²³,Peto Thomas J¹²,Chea Nguon⁴,Chan Davoeung⁵,Mukaka Mavuto¹²,Sirithiranont Pasathorn¹,Dhorda Mehul¹²⁶,Promnarate Cholrawee⁶,Imwong Mallika¹⁷,von Seidlein Lorenz¹²,Duanguppama Jureeporn⁷,Patumrat Krittaya⁷,Huy Rekol⁴,Grobusch Martin P³,Day Nicholas P J¹²,White Nicholas J¹²,Dondorp Arjen M¹²

Affiliation:

1. Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

2. Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom

3. Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical Center, University of Amsterdam, The Netherlands

4. National Center for Parasitology, Entomology and Malaria Control, Phnom Penh

5. Provincial Health Department, Battambang, Cambodia

6. World-Wide Antimalarial Resistance Network, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

7. Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Abstract

In Cambodian villages, 3-month mass drug administration with high coverage using dihydroartemisinin-piperaquine was safe and was followed by the absence of clinical Plasmodium falciparum cases for at least 1 year, despite the presence of multidrug-resistant parasites.

Funder

Bill and Melinda Gates Foundation

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/article-pdf/67/6/817/25632915/ciy196.pdf

Reference36 articles.

1. Evidence of artemisinin-resistant malaria in western Cambodia;Noedl;N Engl J Med,2008

2. Artemisinin resistance in Plasmodium falciparum malaria;Dondorp;N Engl J Med,2009