Real-World Experience With Maribavir for Treatment of Cytomegalovirus Infection in High-Risk Solid Organ Transplant Recipients

Author:

Ni Bin1ORCID,Wolfe Cameron R1,Arif Sana1,Carugati Manuela1ORCID,Heldman Madeleine R1ORCID,Messina Julia A1ORCID,Miller Rachel A1,Saullo Jennifer L1ORCID,Baker Arthur W1ORCID,Maziarz Eileen K1ORCID

Affiliation:

1. Division of Infectious Diseases, Duke University School of Medicine , Durham, North Carolina , USA

Abstract

Abstract We evaluated use of maribavir (MBV) for treatment of 15 episodes of refractory/resistant cytomegalovirus infection in 13 solid organ transplant recipients. Treatment failure due to treatment-emergent MBV resistance or early virological recurrence after MBV discontinuation occurred in 7 (47%) episodes. Sustained viral clearance was achieved in 6 (40%) episodes.

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Oxford University Press (OUP)

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