A Case Study of Zoonotic Chlamydia abortus Infection: Diagnostic Challenges From Clinical and Microbiological Perspectives

Author:

Burgener Anne-Valérie1ORCID,Seth-Smith Helena M B23,Kern-Baumann Sina4,Durovic Ana1,Blaich Anette2,Menter Thomas5,Bruder Elisabeth5,Roloff Tim23,Martinez Aurélien1,Borel Nicole6,Albini Sarah7,Hösli Irene4,Egli Adrian23,Weisser Maja1,Hinić Vladimira2

Affiliation:

1. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel , Basel , Switzerland

2. Division of Clinical Bacteriology and Mycology, University Hospital Basel , Basel , Switzerland

3. Applied Microbiology Research, Department of Biomedicine, University of Basel , Basel , Switzerland

4. Department of Obstetrics, University Hospital Basel , Basel , Switzerland

5. Institute of Medical Genetics and Pathology, University Hospital Basel , Basel , Switzerland

6. Vetsuisse Faculty, Institute of Veterinary Pathology, University of Zurich , Zurich , Switzerland

7. Vetsuisse Faculty, National Reference Centre for Poultry and Rabbit Diseases, Institute for Food Safety and Hygiene, University of Zurich , Zurich , Switzerland

Abstract

Abstract Chlamydia abortus is the most common causative agent of abortion in small ruminants, but it is poorly recognized as a human pathogen. In most published case studies, diagnosis remained difficult and often resulted in delayed initiation of therapy. In this case study of severe C abortus infection in a pregnant farmer from Switzerland, we highlight the clinical and microbiological diagnostic challenges and provide evidence of a zoonotic epidemiological link.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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