Severe Acute Respiratory Syndrome Coronavirus 2 Lethality Did not Change Over Time in Two Italian Provinces

Author:

Flacco Maria Elena1,Acuti Martellucci Cecilia2,Bravi Francesca3,Parruti Giustino4,Mascitelli Alfonso5,Mantovani Lorenzo67,Boccia Stefania89,Manzoli Lamberto1ORCID

Affiliation:

1. Department of Medical Sciences, University of Ferrara, Ferrara, Italy

2. Department of Biomedical Sciences and Public Health, University of the Marche Region, Ancona, Italy

3. “Sant’Anna” University Hospital of Ferrara, Ferrara, Italy

4. Local Health Authority of Pescara, Pescara, Italy

5. Regional Healthcare Agency of Abruzzo, Pescara, Italy

6. School of Medicine and Surgery, University Bicocca, Milan, Italy

7. IRCCS Multimedica, Sesto San Giovanni, Italy

8. Department of Health Sciences and Public Health, Catholic University of the Sacred Heart, Rome, Italy

9. Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

Abstract

Abstract This retrospective cohort study included all the subjects diagnosed with severe acute respiratory syndrome coronavirus 2 infection (n = 2493) in 2 Italian provinces. Two hundred fifty-eight persons died, after a median of 14.0 ± 11.0 days. Adjusting for age, gender, and main comorbidities, the ≥28-day case-fatality rate did not decrease from March to April 2020 (adjusted hazard ratio, 0.93; P = .6).

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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