First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients With COVID-19-Reference-Cited by-同舟云学术

First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients With COVID-19

Published:2021-05-26 Issue:7 Volume:8 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Tantry Udaya S¹,Bliden Kevin P¹,Cho Alastair¹,Walia Naval¹,Dahlen Jeffrey R²,Ens Gordon³,Traianova Malina⁴,Jerjian Christophe¹,Usman Abira¹,Gurbel Paul A¹^ORCID

Affiliation:

1. Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, Maryland, USA

2. Hikari Dx, Inc, San Diego, California, USA

3. Inflammatory Markers Laboratory, Wichita, Kansas, USA

4. CEDx Laboratory, Nashua, New Hampshire, USA

Abstract

Abstract Urine 11-dehydro-thromboxane B2 (u11-dh-TxB2), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and liver-type fatty acid binding protein levels (L-FABP) at the time of hospitalization were higher in coronavirus disease 2019 (COVID-19) patients with adverse events vs without events. Higher u11-dh-TxB2 and L-FABP levels were associated with longer hospitalization, more thrombotic events, and greater mortality, providing evidence for potential utility as early prognostic biomarkers for COVID-19.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofab274/38270552/ofab274.pdf

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