<i>Cryptococcus neoformans–</i>Specific and Non–<i>Cryptococcus neoformans</i>–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis-Reference-Cited by-同舟云学术

Cryptococcus neoformans–Specific and Non–Cryptococcus neoformans–Specific Antibody Profiles in Organ Transplant Recipients With and Without Cryptococcosis

Published:2022-04-20 Issue:7 Volume:9 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Yoon Hyunah¹^ORCID,Nakouzi Antonio¹²,Pappas Peter G³,Hemmige Vagish S¹,Pirofski Liise anne¹²

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center , Bronx, New York , USA

2. Department of Microbiology and Immunology, Albert Einstein College of Medicine , Bronx, New York , USA

3. Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama , USA

Abstract

Abstract Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely associated with cryptococcosis status, and may hold promise as markers of cryptococcosis.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofac211/43402013/ofac211.pdf

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