Sex-Based Disparities in the Transition to Dolutegravir-Based Antiretroviral Therapy in West African HIV Cohorts
Author:
Tiendrebeogo Thierry1ORCID, Malateste Karen1, Poda Armel2ORCID, Minga Albert3ORCID, Messou Eugene456, Chenal Henri7, Ezechi Oliver8, Ekouevi Didier K19ORCID, Ofotokun Igho10ORCID, Jaquet Antoine1, , Zannou Marcel Djimon, Poda Armel, Ezechi Oliver, Messou Eugene, Chenal Henri, Minga Kla Albert, Tanon Aristophane, Seydi Moussa, Mensah Ephrem, Yonaba Caroline, Tossa Lehila Bagnan, Dame Jocelyn, N’Gbeche Sylvie Marie, Kouakou Kouadio, Folquet Madeleine Amorissani, Eboua François Tanoh, Traore Fatoumata Dicko, David Agatha, Takassi Elom, Jaquet Antoine, Ekouevi Didier Koumavi, Dabis François, Becquet Renaud, Bernard Charlotte, Malateste Karen, Marcy Olivier, Plaisy Marie Kerbie, Rabourdin Elodie, Tiendrebeogo Thierry, Dahourou Désiré, Desmonde Sophie, Jesson Julie, Leroy Valeriane, Moh Raoul, Azani Jean-Claude, Koffi Jean Jacques, Komena Eric, Bengali Maika, Cissé Abdoulaye, Gnepa Guy, Horo Apollinaire, Boni Simon, Kangah Eulalie, Moh Corinne, Eliam Jeanne, Ofotokun Ighovwerha, Martin Chris, Benzekri Noelle, Goettlieb Geoffrey, Keiser Olivia, Jaquet Antoine, Ekouevi Didier, Ofotokun Ighovwerha, Becquet Renaud, Benzekri Noelle, Bernard Charlotte, Boni Simon, Dabis François, Dahourou Désiré, Desmonde Sophie, Ekouevi Didier Koumavi, Jaquet Antoine, Jesson Julie, Komena Eric, Leroy Valeriane, Malateste Karen, Ofotokun Ighovwerha, Plaisy Marie Kerbie, Rabourdin Elodie, Tiendrebeogo Thierry
Affiliation:
1. National Institute for Health and Medical Research UMR 1219, Research Institute for Sustainable Development EMR 271, Bordeaux Population Health Research Centre, University of Bordeaux , Bordeaux , France 2. Department of Infectious Diseases, Université Nazi Boni , Bobo-Dioulasso , Burkina Faso 3. Centre médical de Suivi des Donneurs de Sang, Centre National de Transfusion Sanguine Côte d’Ivoire , Abidjan , Côte d’Ivoire 4. Centre de Prise en charge de Recherche et de Formation , Abidjan , Côte d’Ivoire 5. Programme PACCI/ANRS Research Center , Abidjan , Cote d’Ivoire 6. Département de Dermatologie et d’Infectiologie, Unite de Formation et de Recherche des Sciences Médicales, Université Félix Houphouët Boigny , Abidjan , Côte d’Ivoire 7. Virology Laboratory, Integrated Centre for Bioclinical Research in Abidjan , Abidjan , Côte d’Ivoire 8. Office of the Central Secretariat, Nigeria Institute for Medical Research , Lagos , Nigeria 9. Département de Santé Publique, Université de Lomé , Lomé , Togo 10. Division of Infectious Diseases, Department of Medicine, School of Medicine, Emory University , Atlanta, Georgia , USA
Abstract
Abstract
Transition to dolutegravir among 21 167 individuals experienced in antiretroviral therapy in West Africa showed heterogeneous timelines and patterns. Initially reported sex disparities tended to catch up over time with persisting disparities, according to contributing HIV clinics. Key factors facilitating dolutegravir switch were male sex, age <50 years, viral suppression, and regimens not based on protease inhibitors.
Funder
US National Institutes of Health National Institute of Allergy and Infectious Diseases Eunice Kennedy Shriver National Institute of Child Health and Human Development National Heart, Lung, and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases National Institute on Drug Abuse National Institute on Alcohol Abuse and Alcoholism Fogarty International Center National Cancer Institute
Publisher
Oxford University Press (OUP)
Cited by
1 articles.
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